Showing posts with label infertility protocol. Show all posts
Showing posts with label infertility protocol. Show all posts

Sunday, November 2, 2014

Egg Retrieval Set

I spoke with Dr. D and as expected, we are a go for triggering tonight. I'll be doing my Novarel (HCG) trigger shot at 12:15am tonight/tomorrow morning and my retrieval will be Tuesday at 12:15pm.

Dr. D went over my follicles with me and made me feel a little better about the ones we've got. He feels that since we got 4 solid embryos from our 4 best follies last cycle that it's perfectly reasonable to believe that these top 4 follicles will have healthy mature eggs in them that could be our next 4 embryos. It's an optimistic viewpoint and I'm choosing to share it and believe that these are the ones.

The prime three are the 20, 22 and 22. The 26 might be a little overcooked but the 17 could catch up between the trigger and retrieval, it's very possible. I'd like to see it at least 18 or 19 on retrieval day but I don't think they bother with measuring, he'll just take everything he sees.

I've definitely got stuff going on in there too, I'm hungry, beyond exhausted, still have that friggin' pressure head ache and feel all sorts of twingey cramping around my uterus. My ovaries don't feel too uncomfortable, no huge grapefruit feeling, so I think the estrogen the follies are putting out is to blame for the random sharp twinges in my lower belly. And I still have to pee over and over.

Now I just need to stay awake for my trigger! I've got an alarm set just in case but I think I'll be okay. I've been trying to nap all day without success so I just keep yawning and dragging my feet. We're so close, we just need to make it through this retrieval, get some healthy test results, and have a successful FET.

Monday, October 27, 2014

Less Than Awesome Ultrasound

So this mornings ultrasound appointment was less than ideal. At this point in our first IVF cycle, we had at least 8 follies 10-13mm and a 9th slightly smaller than 10mm. Today we had only 5 follicles in the 10-14mm range, 3 follicles a bit less than 10mm and 2 less than 5mm. My right side, which is usually my best producer, is basically crapping out at the moment and I'm super disappointed in it.
I was hoping for a bit better :(
Every cycle is different so it's really tough to compare one to another but I can't help over analyzing everything I've done differently. For example, I suppressed for two days longer. I took Tylenol for cramps while on my birth control pills and tums for heart burn.  I was late yesterday for my shot by 30 min. I'm taking the higher, correct dose of Omnitrope. I'm using Italian Menopur instead of UK Menopur.

Realistically, I think the difference is probably from the extra birth control but there's nothing I can do at this point. I just have to hope that a few more follies pop up and the ones we can see grow into beautiful, healthy, mature eggs. I'm going to be adding in my Cetrotide tomorrow since the follies weren't big enough today and my next appointment will be Wednesday. Fingers and toes crossed!

Sunday, October 26, 2014

Zonked Out

Today I am completely and totally zonked out. I think I felt okay for the first couple hours of the day but since then I've been exhausted. My head and eyes feel so heavy, I feel like I could sleep the whole day away and still be tired.

Although the medication dosages have been exactly the same, I'm definitely getting side effects earlier with this second cycle of IVF.  With the first, it was probably a good week of stims before I felt any different than a slightly poked version of normal. This time, it only took about 2 days for me to start getting heartburn and bloating and now that we're on day 6, I'm so, so tired.  An exhausted, half asleep lump who looks like they swallowed a fat, firm balloon.

I'm so thrown off that I was actually late for my shot this evening. Since starting the IVF process, I've been vigilant about keeping on top of my injections. My alarm goes off at 9am/pm, I immediately grab supplies and prep my shots, and they're done by 9:30am/pm. This evening, I managed to get everything wrong. I was so tired I could barely stay awake so I took Milou for a nice walk in the finally cool, fall air. I came back at 8:40pm, thinking about my shot with a solid 20 minutes to spare, and then got distracted by a phone call from E.

E was on his way home from work and was hungry. I checked the fridges and cabinets but we didn't have anything that could be easily prepared for dinner. I then had the wonderful idea to give my sister L a ride home from her restaurant and bring home Japanese food. Sounds good right? Delicious food, no prep, easy peasy! Except somewhere in there I'd completely forgotten about my shot.  And then my evening shot event was somehow deleted from my calendar, which means no alarm. Whoops.

I was sitting outside L's restaurant, listening to my Harry Potter audio book for the 5 millionth time, when I looked down at my clock and saw 9:30pm. It took a few minutes to click

...huh, it's 9:32, hope she gets out soon, I'm hungry....9:37...huh...FUCK!

I freaked out a bit, called E who reminded me not to freak out, and then shortly thereafter my sister got off work. I zoomed home as fast as I could, skipped getting the delicious froyo I was planning to buy,  prepped the shot and finally got it done by about 10:05, half an hour late. My beef was stone cold by the time I got to it and I'm still upset with myself and completely exhausted again.

How could I forget for even a second that nothing is normal when you're doing IVF -_- Everything runs on such a strict schedule and here I am acting like I can go do whatever I feel like. Blah. I'm going to go sleep now so I don't accidentally miss my morning shot and next appointment.

Friday, October 24, 2014

Easy Peasy Fix and Oodles of Follies!

This morning was my stim day 4 appointment and we got surprisingly good news all around! Since Friday and Monday seem to be the clinic's busy days, there was a decent line for ultrasounds and blood work and I decided to go up to the financial office first. I hadn't received a call back from my contact yet but when I went up to her office she had already listened to my message and was ready to help.

As I already knew, everything on the estimate was incorrect. She took the aCGH testing off first since we are paying Reprogenetics direct and then corrected the third cycle ICSI to the second cycle price. I thought she might go back on her earlier statement about only paying the biopsy fee once but she didn't! She looked up the payment records, saw that we'd already paid it once, and took it right off the bill. I have to admit, I was impressed. I was expecting a lot more push back for what turned out to be a 5 minute conversation. Basically, I was working myself up, worrying about nothing. Whoops.


I would have just paid for the ICSI today since I had the estimate in hand, but our credit card company has helpfully decided to replace my card due to "potential fraud". As one might guess, the potential fraud they're referring to is my charge to IVFmeds.com, a charge that I had already spoken to a supervisor about and approved. This still wasn't good enough for them so I'm now waiting on a new card to come in the mail, and my old one will only work if they're swiping it directly, which neither SCRC nor Reprogenetics would do. Given the hassle, I figure it's better to wait and give them a card they can actually run.

With that all sorted out for the time being, E and I went down to my ultrasound and even more good news. Both my left and right ovary each had 6 tiny follicles, for a total of 12 follies after only 4 (really 3.5) days of stims! The largest on the left was 8mm with the largest right following just behind at 7mm. This means the follicles are well synced and will hopefully continue to grow at the same rate so they can all mature together. If you recall, I wrote about last cycles stim day 4 ultrasound here and I only had 8 follies visible at that appointment. I did an extra two days of suppression for this cycle so I'm not surprised these follies were a bit smaller but I certainly wasn't expecting to have an extra four right from the get go!

What I'm wondering now, is whether or not I'll have to stim longer than last cycle to give these follies more time to mature their payload. Are two extra days of suppression enough to require an additional day or two of stims? I already have to order a third cartridge of Omnitrope, with the adjusted dosage the two cartridges I bought will only last about 8 days and I'm anticipating needing enough for at least 11-12 days. I don't know if I'll get lucky enough to have Kaiser cover this last vial like the did the other two, but it would be seriously wonderful if they could.
Please order more things. I don't have enough boxes!
My next round of ultrasound/labs will be on Monday so in the meantime, I'll try to send lots of positive, growing thoughts to my follies. We want to keep them all growing nice and evenly so they're perfectly mature and ready to be fertilized after retrieval.

Saturday, October 18, 2014

Round Two is a Go!

This morning I had my official baseline ultrasound and lab work to make sure the birth control has done it's job. The tech who was so good last cycle couldn't find the vein in my right arm and gave up after repositioning the needle six times. She prepped my left arm, which is my less cooperative side, but gave up without trying when that vein didn't pop up either. The only option left was my hand which always stings in the weirdest way, but is at least easy to find. 

According to the ultrasound, my ovaries are nice and quiet, successfully suppressed! My lab work confirmed the suppression so we are officially cleared to start IVF number 2!

Fist pumping kitty approves!
Although it's only been about 4 weeks, I think I'll call Reprogenetics for a progress report on Monday. I know the probe won't be finished yet, but it will make me feel better to hear that there's progress happening. 

In terms of protocol, my last birth control pill was yesterday so I'll start stims on Tuesday morning. I've got everything ready to go except my Novarel which I don't need for a couple of weeks. Everything is falling into place and I'm predicting a November 3rd retrieval date.

Deep breath, cross my fingers, and here we go again!

Tuesday, October 14, 2014

IVF Meds Package!

Look what finally arrived! My first batch of meds for this cycle :) I would have had them yesterday but it was Columbus Day and I completely forgot that there was no mail. Since I have to sign for the package or they won't leave it, I worked my schedule so I could be home today. Then I waited. 

And waited.

Annnnnd waited. 

All Day!

My other two packages from IVFMeds came at 10am and 2pm. This package didn't come until FIVE! I could have done a million other things not the least of which would have been to pick up my Kaiser order which is still sitting and waiting for me at the pharmacy.

This batch of Menopur came in blue boxes labeled "MeRopur". The last batch came in pink boxes labeled "MeNopur", the left overs are in the bottom right corner of the photo. A quick google search told me that it's the exact same medicine, by the exact same company, but its from the lot distributed to Italy where they call it Meropur instead of Menopur. Apparently the word or pronunciation of "Menopur" in Italian translates to something like "Not Yet" which Ferring thought would have a negative connotation. I opened each box to inspect them and make sure none broke in transit and the actual vials themselves appear to be the same vials, with the same med pellet but with different labels. 

The 5 Cetrotide were the exact same as last time, little kits with a vial of powder and a pre-filled syringe. The remaining 43 Menopur vials are on their way from London to New York right now and I'm curious to see whether they'll be Menopur or Meropur. I might call and ask but I don't think it makes a difference either way.

Saturday, October 11, 2014

IVF Meds Take Two!

Now that the stim start date is inching closer and closer, I went ahead and placed my order for the next round of IVF! Since we had such good success with IVFMeds.com last time and the meds are SO MUCH CHEAPER, we went with them again. Even with the good amount left over from the extra we had to buy for last cycle I still had to order a tooooon of Menopur.

Thanks IVFMeds.com for saving me a ton!

Last cycle I had some extra Menopur left over from my second IUI and even with that extra, I still used a few of the last minute Menopur order. If this cycle is anything like last time, they expect me to use 90+ vials and stim for at least 11 days so I'm ordering over 80 vials of Menopur. Since I was one short last time, I also ordered 5 Cetrotide injections and hopefully that will be enough.

After the second batch of meds took a bit longer than was ideal to get here last time, IVFMeds.com offered to credit me the difference in cost for the extra vials I didn't use. I was skeptical because come on,  that's really excellent custom service, much more than I would expect from an online company based in another country. Instead of placing my order online, I rang up customer service and got the same wonderful rep that helped me last cycle. He remember me and my order snafu and in just a few minutes was placing my new order with a credit for the difference in the extra vials.  I'm still kind of shocked! It was all quick and easy, I rang them up, rang the bank to authorize the transaction since it got flagged again, and my nurse emailed me the new scripts to upload only minutes later. After all the calling and price checking and back and forthing of last cycle, I never knew the process could be so smooth.  

Impossible to beat these prices!

They're moving like ninjas this time and have already shipped out the first batch of my order, 40 Menopur and 5 Cetrotide. Like last time, I ordered so much Menopur that their pharmacy can't fill it all at once from in store stock so they're shipping it in two separate batches. This order went out on Friday so I'm not quite sure when to expect it. Priority Mail Express International does a lot of things regular Priority doesn't do, it's even delivered by a separate branch of USPS. If the package moves on Sunday, it should arrive in New York tomorrow and will probably be delivered by Monday. If it doesn't travel on Sunday, it'll hit the big apple on Monday and I'll get it Tuesday.  I also have to call Kaiser to authorize them ordering my Omnitrope and needles/syringes. The order was called in on Friday but from past experience I know they won't actually order it until I ask for it.

It doesn't make a difference protocol wise if the Menopur arrives on Monday or Tuesday since I don't need it just yet, but since I have to be here to sign for it in person, I have to plan my schedule around the delivery. Kind of a pain but well worth the savings!