My progesterone has been increasing pretty consistently at a "low normal level" as my pregnancy progresses, which the RE has been happy with since the transfer was natural. With PIO, they'd be looking for levels over 20 early on and a big jump when the placenta takes over. As you can see, the biggest bump I've had was 16.6 a couple hours after I'd put my progesterone in.
I am supposed to be weaning off the Endometrin since I'm 11 weeks today but my labs at 10w5d showed my progesterone was only 15.4. I would have thought that my placenta would have taken over and be producing progesterone on it’s own by now, but it’s not making the jump. The RE isn’t super concerned since this is still technically the lowest side of normal and my estrogen is increasing, but I am freaking out. There's all sorts of studies suggesting that "91% of pregnancies with progesterone lower than 15 ng/ml will end in miscarriage" (source) and "Average progesterone in pregnancies that miscarry is 14 ng/ml; in healthy pregnancy: 32 ng/ml" (source). I'm terrified that my levels are low enough to endanger our otherwise perfectly healthy baby.
I know some women just have lower progesterone but I don’t feel ready to stop the Endometrin without a real increase. I only have 1 day of Endometrin left and I just don't feel good about stopping.
